Effectiveness evaluation of radiosynovectomy on the radiological progression of osteoarthritis of the knee joint
Imre Szerb1, Tamás Gál2, László Hangody1, Ibolya Mikó3
1Department of Orthopaedics and Traumatology, Uzsoki Hospital, Budapest
2Department of Traumatology, Semmelweis University, Budapest
3National Institute of Rheumatology and Physiotherapy, Budapest
Keywords: Osteoarthritis; radiosynovectomy; synovectomy; synovitis.
Objectives: This study aims to analyze the effect of radiosynovectomy (RSO) on the radiological progression of osteoarthritis of the knee joint.
Patients and methods: The study included 207 knee joints of 181 patients (72 males, 109 females; mean age 58 years; range, 19 to 65 years) that were performed RSO between 01 April 2003 and 31 December 2015 in the Department of Orthopedics and Traumatology at Uzsoki Hospital. A total of 111 right and 96 left knees were treated. The mean duration of follow-up was 8.7 years (range, 1 to 12 years). Of the 181 patients, both knee joints were treated in 26.
Results: Of the 207 treated knee joints, 163 had the same Kellgren-Lawrence grade at the time of follow-up compared to the grade at the time of RSO, while 44 had worse outcomes. This indicated that radiological progression was not present in 79% of the treated knee joints. The intraclass correlation coefficient (ICC) showed significantly strong agreement between the pre- and post-measurements (ICC=0.835, p<0.001).
Conclusion: Radiosynovectomy was able to impede radiological progression in 79% of the treated joints and only one-grade deterioration was observed in 39 cases during follow-up.