Endobronchial pulmonary metastasis in malignant tenosynovial giant cell tumor: A rare cause of central airway obstruction
Ipek Çalık1
, Canberk Canayakın1, Şule Kevser Dursun2, Nur Büyükpınarbaşılı2, Mehmet Akif Özgül1
1Department of Pulmonology, Başakşehir Çam ve Sakura City Hospital, İstanbul, Türkiye
2Department of Pathology, Başakşehir Çam ve Sakura City Hospital, İstanbul, Türkiye
Keywords: Endobronchial metastasis, malignant, orthopedic oncology, pulmonary metastasis, tenosynovial giant cell tumor.
Abstract
Tenosynovial giant cell tumor (TGCT) is a rare mesenchymal neoplasm arising from the synovium, tendon sheath, or bursa. Although the localized and diffuse forms of TGCT are typically considered benign, malignant TGCT characterized by marked histologic atypia and increased mitotic activity may exhibit aggressive clinical behavior. Pulmonary metastasis from malignant TGCT is rare and, in previously reported cases, pulmonary involvement has predominantly been described as parenchymal nodules or pleural lesions. In this article, we describe a rare case of endobronchial pulmonary metastasis occurring approximately 72 months after the initial diagnosis of malignant TGCT originating from the tendon sheath of the knee.
Citation: Çalık I, Canayakın C, Kevser Dursun Ş, Büyükpınarbaşılı N, Özgül MA. Endobronchial pulmonary metastasis in malignant tenosynovial giant cell tumor: A rare cause of central airway obstruction. Jt Dis Relat Surg 2026;37(3):882-885. doi: 10.52312/ jdrs.2026.2787.
I.C.: Idea/concept, design; M.A.O.: Control/supervision, analysis and/or interpretation; C.C., S.K.D., N.B.: Data collection and/or processing; I.C., C.C.: Literature review, writing the article; M.A.O.: Critical review; I.C., C.C., S.K.D., N.B.: References and fundings; S.K.D., N.B., M.A.O.: Materials.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
The authors also acknowledge the institutional support provided by the Department of Pulmonology.
The authors thank the interventional pulmonology nurses and technical staff of Basaksehir Cam ve Sakura City Hospital for their valuable assistance during the bronchoscopic procedure.
The data that support the findings of this study are available from the corresponding author upon reasonable request.
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