Comparison between unilateral curved and bilateral straight percutaneous vertebral augmentation in the treatment of osteoporotic vertebral compression fractures: A meta-analysis
Xin Fu1*, Yao-min Li2*, Peng Tian3, Gui-jun Xu1, Zhi-jun Li4
1Department of Orthopedics, Tianjin Hospital, Tianjin, China
2Department of Rehabilitation, Tianjin Hospital, Tianjin, China
3Department of Traumatic Orthopedics, Tianjin Hospital, Tianjin, China
4Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China
Keywords: Meta-analysis, osteoporotic vertebral fractures, percutaneous, vertebral augmentation.
Objectives: The aim of this meta-analysis was to compare the efficacy and safety of unilateral curved and bilateral straight percutaneous vertebral augmentation (PVA) in the treatment of osteoporotic vertebral compression fractures (OVCFs).
Materials and methods: We performed a comprehensive literature search from electronic databases including Springer, Web of Science, PubMed, Cochrane Library databases and ScienceDirect up to July 2022. Three randomized-controlled trials (RCTs) and one retrospective study which met the inclusion criteria were analyzed.
Results: There were significant differences in the operative time, injected bone cement volume, bone cement leakage rate and X-ray frequency between the bilateral straight PVA and unilateral curved PVA. No significant differences were found regarding postoperative Cobb angle, Visual Analog Scale or Oswestry Disability Index between the two groups.
Conclusion: Compared to bilateral straight PVA, unilateral curved PVA may decrease operative time, injected bone cement volume, bone cement leakage rate, and X-ray frequency in the treatment of OVCFs. However, the Cobb angle, pain, and clinical scores are comparable. Due to the limited quality and data of the evidence currently available, more high-quality RCTs are required.
* The first two authors contributed equally to this manuscript.
Citation: Fu X, Li YM, Tian P, Xu GJ, Li ZJ. Comparison between unilateral curved and bilateral straight percutaneous vertebral augmentation in the treatment of osteoporotic vertebral compression fractures: A meta-analysis. Jt Dis Relat Surg 2023;34(2):237-244. doi: 10.52312/jdrs.2023.967.
No ethical approval was required, as all data in this meta-analysis were derived from previously published research. The study was conducted in accordance with the principles of the Declaration of Helsinki.
Data Sharing Statement:
The data that support the findings of this study are available from the corresponding author upon reasonable request.
All authors contributed equally to the article.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
The authors received no financial support for the research and/or authorship of this article.
The authors are grateful for the support by Tianjin Health Science and Technology Project (No. ZC20096 and RC20120).