İhsan Akan1, Tayfun Bacaksız1, Naim Özpolat2, Mahmut Tunçez1, Cemal Kazımoğlu1

1Department of Orthopedics and Traumatology, Izmir Katip Çelebi University Faculty of Medicine, Izmir, Türkiye
2Department of Orthopedics and Traumatology, Balıklıgöl State Hospital, Şanlıurfa, Türkiye

Keywords: Bone defects, immediate fixation, induced membrane technique


Objectives: This study aimed to evaluate the treatment outcomes of patients treated with induced membrane technique (IMT) for the reconstruction of bone defects and to identify factors associated with the success and failure of the modified technique.

Patients and methods: Between January 2016 and April 2021, a total of 23 adult patients (20 males, 3 females; median age: 39.9 years; range, 20 to 69 years) who underwent bone reconstruction using the IMT for established pseudoarthrosis and acute bone loss were retrospectively analyzed. Fracture type, the size and location of bone defect, the nature of the index injury, the type of fixation, the interval between stages of the operation, and any diagnosis of infection or other complications of the patients were assessed.

Results: The median bone union was achieved in 6.6 (range, 4 to 11) months. The median index of reconstruction was 19 (range, 10 to 30%). The main complications were recurrent infection in two cases and nonunion in one case. Massive graft resorption occurred in two cases.

Conclusion: Immediate internal fixation is a reliable and effective method in the treatment of complex bone defects. A large volume of autograft is required for the reconstruction of long defects, which presents as a limiting factor, particularly in patients undergoing previous surgical interventions.

Citation: Akan I, Bacaksız T, Özpolat N, Tunçez M, Kazımoğlu C. Is immediate internal fixation safe in induced membrane technique?. Jt Dis Relat Surg 2023;34(1):151-157. doi: 10.52312/ jdrs.2023.829

Ethics Committee Approval

The study protocol was approved by the Katip Çelebi University Local Ethics Committee (date: 21.04.2022, no: 214). The study was conducted in accordance with the principles of the Declaration of Helsinki.

Author Contributions

Provided input into the concept and design of the study, and provided the materials, analyzed the data, carried out literature review: İ.A., T.B.; Collected and assembled the data: N.P., M.T.; Wrote the article: İ.A., C.K.; All authors have critically revised the article, read and approved the final version at the time of submission.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.